Suggested Literature
The following links, articles and reviews provide a window to discover the potential of alternative research models. This list is far from exhaustive and intend to be used as a starting point to further literature research.
Non-mammalian animal models
Howe, Kerstin et al. “The zebrafish reference genome sequence and its relationship to the human genome.” Nature vol. 496,7446 (2013): 498-503. doi:10.1038/nature12111
White, Richard M, and E Elizabeth Patton. “Adult zebrafish as advanced models of human disease.” Disease models & mechanisms vol. 16,8 (2023): dmm050351. doi:10.1242/dmm.050351
Rotstein, Barbara, and Achim Paululat. “On the Morphology of the Drosophila Heart.” Journal of cardiovascular development and disease vol. 3,2 15. 12 Apr. 2016, doi:10.3390/jcdd3020015
Souidi, Anissa, and Krzysztof Jagla. “Drosophila Heart as a Model for Cardiac Development and Diseases.” Cells vol. 10,11 3078. 8 Nov. 2021, doi:10.3390/cells10113078
Hales, Karen G et al. “Genetics on the Fly: A Primer on the Drosophila Model System.” Genetics vol. 201,3 (2015): 815-42. doi:10.1534/genetics.115.183392
“Drosophila Methods and Protocols”, edited by C. Dahmann (Springer New York, New York, NY, 2016). doi:10.1007/978-1-4939-6371-3
Corsi, Ann K et al. “A Transparent Window into Biology: A Primer on Caenorhabditis elegans.” Genetics vol. 200,2 (2015): 387-407. doi:10.1534/genetics.115.176099
Unicellular models
Williams, Robin S B et al. “Towards a molecular understanding of human diseases using Dictyostelium discoideum.” Trends in molecular medicine vol. 12,9 (2006): 415-24. doi:10.1016/j.molmed.2006.07.003
Gruenheit, Nicole et al. “Mutant resources for functional genomics in Dictyostelium discoideum using REMI-seq technology.” BMC biology vol. 19,1 172. 24 Aug. 2021, doi:10.1186/s12915-021-01108-y
Organoid-type models
Miura, Yuki et al. “Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells.” Nature biotechnology vol. 38,12 (2020): 1421-1430. doi:10.1038/s41587-020-00763-w
Andersen, Jimena et al. “Generation of Functional Human 3D Cortico-Motor Assembloids.” Cell vol. 183,7 (2020): 1913-1929.e26. doi:10.1016/j.cell.2020.11.017
Faustino Martins, Jorge-Miguel et al. “Self-Organizing 3D Human Trunk Neuromuscular Organoids.” Cell stem cell vol. 26,2 (2020): 172-186.e6. doi:10.1016/j.stem.2019.12.007
Lancaster, Madeline A et al. “Guided self-organization and cortical plate formation in human brain organoids.” Nature biotechnology vol. 35,7 (2017): 659-666. doi:10.1038/nbt.3906
Cell culture-based models
McTague, Amy et al. “Genome Editing in iPSC-Based Neural Systems: From Disease Models to Future Therapeutic Strategies.” Frontiers in genome editing vol. 3 630600. 15 Mar. 2021, doi:10.3389/fgeed.2021.630600
Lines, Georgie et al. “Modelling frontotemporal dementia using patient-derived induced pluripotent stem cells.” Molecular and cellular neurosciences vol. 109 (2020): 103553. doi:10.1016/j.mcn.2020.103553
Capano, Lucia S et al. “Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons.” Cell stem cell vol. 29,6 (2022): 918-932.e8. doi:10.1016/j.stem.2022.04.018
Arber, Charles et al. “Stem cell models of Alzheimer’s disease: progress and challenges.” Alzheimer’s research & therapy vol. 9,1 42. 13 Jun. 2017, doi:10.1186/s13195-017-0268-4