The Best Models Working Group stems from the clearly stated commitment to the 3Rs that is defined within the remit of the Network. The group defines the strategy for replacement opportunities within ongoing and future projects and takes responsibility for articulating, whenever appropriate, the reasons as to why replacements may not be available in specific circumstances.
Gathering and disseminating information on resources in other model systems or organisms is another key element of the group’s work, together with highlighting technological or knowledge gaps within the Network that might hinder the use of other models.
Finally, the group is active in seeking areas of funding for replacement pilot studies for the Network and in disseminating the current ethical review process associated with MLC’s and Network’s projects.